Orlistat has been shown to cause mild side effects in some individuals. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious effects, seek medical attention immediately.
Common side effects of orlistat use include:
More serious side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a serious adverse reaction–or allergic reaction–to this medication and require treatment right away.
Orlistat has been shown to affect the absorption of fat-soluble vitamins (vitamin A, D, E and K). This can prevent individuals taking this medication from receiving valuable nutrients from their food. Your doctor may recommend that you take a multivitamin and beta-carotene supplement along with this medication to ensure that you are receiving adequate nutrition from the food you eat.
As with all medication, inform your health care provider of any medical conditions you are currently managing. Let them know if you have or ever had kidney stones, diabetes, liver disease, gallbladder disease, thyroid disease, or an eating disorder (anorexia or bulimia). In addition, you should tell them if you have ever had an organ transplant, cholestasis (reduced or stopped bile flow), or malabsorption syndrome.
Tell your provider about any and all medication, prescription drugs, and supplements you are taking before starting treatment with orlistat. Orlistat can interact with substances in the body, causing potentially serious adverse reactions. Specifically, you should inform them of any immunosuppressant medication you are currently taking, such as cyclosporine. You should also let your provider know if you are currently taking blood thinners–like warfarin–or diabetes medication–like metformin.
In addition, let your doctor know if you are planning to become pregnant, are pregnant, or are currently breastfeeding before starting treatment with this medication.
paralysisIn addition to side effects, let your doctor know if you are having liver disease before starting treatment with this medication or have any liver disease. Some liver problems include hematemesis, perhousingh failure, and pernicious aneuisne. If you experience any of these, your doctor may need a stop-AY treatment.
In addition, let your doctor know if you are over 50 years of age or if you have active liver disease. Also, let your doctor know if you are a women, children, or if you are having a vaginal yeast infection. Otherwise, let your doctor know. A reputable medical professional can provide free blood tests to ensure this medication is being used properly.
Tell your doctor if you are not sure whether you are orlistat and if you have any upcoming genetic tests. Even if you are new to the medication, some individuals may be more sensitive to specific side effects of orlistat.anoia/antifungal
DizzinessThis medication has been shown to increase the risk of developing a high temperature (fever, chills) and easy bruising or stinging in the stomach. If you experience any of these symptoms, contact your doctor immediately.
Lipase is a lipase inhibitor, which is a potent lipase inhibitor that is structurally related to androgen receptor and is structurally similar to the other lipase inhibitors (e.g., apixaban, clofibric). A recent study identified the clinical effect of androgen receptor antagonism in the treatment of patients with severe obesity and overweight with or without comorbidities.
This study aimed to investigate the clinical effect of orlistat, a drug used to treat obesity in adults, on weight change.
A total of 1640 adult patients with obesity were enrolled, of whom 1,531 patients had diabetes mellitus and 1,746 patients had hypertension. All patients were treated with orlistat at a dose of 120 mg once daily for 28 days. All patients were assessed on a questionnaire, the World Weight Loss Association (WWA) scale, body mass index (BMI) and waist circumference. All patients were followed up for at least 6 months (see ) in case of any clinically significant change.
Patients were divided into 3 groups according to the dose: 120 mg once daily, 120 mg once daily, and placebo. The mean change in BMI and waist circumference was greater in the placebo group (3.6 vs. 3.1, respectively). A statistically significant increase in body weight was observed in the 120 mg and placebo groups (p <0.001).
In this study, the average change in BMI was greater in the 120 mg and placebo groups (p <0.001), whereas the average change in waist circumference was less in the placebo group (p <0.001).
In patients with diabetes mellitus and hypertension, there was a statistically significant difference between orlistat dose (p <0.001) but not with the placebo (p >0.05).
Orlistat and other antiobesity drugs like placebo are effective and well tolerated in patients with obesity, and they produce weight loss that is reversible and is maintained. However, patients should be advised to report any clinically significant weight loss after discontinuation of the drug. Moreover, caution is needed when prescribing orlistat to patients with obesity.
Citation:Lambert-Gonzalez S, Humberto M, Guedes E, et al. (2023) Randomized, open-label trial of orlistat in obese patients: The efficacy of orlistat for weight management in patients with overweight or obesity. PLoS ONE 24(9): e0112093. https://doi.org/10.1371/journal.pone.0112093
Editor:Leopold C. A. Guedes, University of California, San Francisco, USA
Received:February 19, 2019;Accepted:June 10, 2019;Published:June 21, 2019
Copyright:© 2019 Lambert-Gonzalez et al. This is an open-access article distributed under the terms of the, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding:This work was supported by the National Institutes of Health (NIH), National Institutes of Health Clinical Fellowship to Guedes E, and by a grant from the National Heart, Lung, and Blood Institute (NHLBI). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests:The authors have declared that no competing interests exist.
Obesity is a growing global epidemic of obesity and overweight, which has been linked to health issues such as cardiovascular disease, type 2 diabetes, and high blood pressure. A meta-analysis of randomised controlled trials (RCT) of orlistat showed an increased risk of type 2 diabetes mellitus and cardiovascular disease in patients with obesity []. In addition, the efficacy of orlistat for obesity treatment has been investigated by many research groups, including a meta-analysis of clinical trials of orlistat []. However, it is not known whether orlistat is effective for weight management. In addition, there is limited evidence to support its use [].
Orlistat 120mg Capsules, Pack of 3, is a weight loss medication that is used to help people lose weight when combined with a reduced-calorie diet and exercise program. These capsules are taken by mouth, with or without food, once a week.
Orlistat is a lipase inhibitor, which means it blocks the absorption of fat in the body. By preventing the absorption of fat, it helps the body to remove some from the body, which is then converted into another substance in the body. This is achieved by blocking the absorption of about 30% of the fat consumed in a meal, and about 55% by the entire meal.
Orlistat is only available with a reduced-calorie diet and an active exercise program. It is only available with a reduced-calorie diet and an exercise program.
The active ingredient in Orlistat is orlistat. Other ingredients in Orlistat include colloidal silicon dioxide, croscarmellose sodium, hydroxypropyl cellulose, magnesium stearate, and microcrystalline cellulose.
What is weight loss treatment?
Orlistat 120mg Capsules, Pack of 3 are a prescription weight loss medication that is used to help people lose weight when combined with a reduced-calorie diet and exercise program. These capsules are taken by mouth with or without food, for by-e-mail use. Orlistat 120mg Capsules, Pack of 3 are only available with a reduced-calorie diet and an active exercise program.
Orlistat 120mg Capsules, Pack of 3 can cause side effects, although not everyone experiences them. The most common side effects of Orlistat 120mg Capsules, Pack of 3 include:
Orlistat can cause digestive problems, though not everyone gets these side effects. If you experience any of the following symptoms, stop using this medication and contact your doctor immediately:
Contact your doctor immediately if any of the following symptoms get worse, or if do not get better after a few days, contact your doctor:
If you are allergic to orlistat or any of the other ingredients of this medication, stop using this medication and contact your doctor immediately:
Orlistat 120mg Capsules, Pack of 3 is for use by adults and children of 12 years and older. It can be taken with or without food. However, it is recommended to take this medication at least 30 minutes before any weight loss activity, and the duration of treatment is also important.
The capsule may be taken with or without food, and should be taken twice daily, or three times daily. It is recommended to take this medication at the same time every day.
The Orlistat market is a key player in the global market for andlistat, a prescription weight loss aid. This medication is approved by the US Food and Drug Administration (FDA) to be used for weight loss by the body.
The Orlistat market is highly competitive. The market is growing at a rate of approximately 8.5% per year.
A total of 10 major pharmaceutical companies (Bayer, AstraZeneca, Bristol-Myers Squibb, GlaxoSmithKline, Merck Kline, Novartis) are actively involved in the Orlistat market. The total market size is estimated to be USD 3.2 billion by 2021, growing at a rate of approximately 3.1% per year.
For more detailed insights about the Orlistat market, please visit.
The Orlistat market is segmented based on the regions: North America, Europe, Asia Pacific, Latin America, Middle East and Africa, and the Middle East & Africa. North America is the largest market in the market, followed by Europe by Asia Pacific.
The Orlistat market segmentation is influenced by several factors, such as the product type, dosage forms and consumer preferences. The market size for the Orlistat market is estimated to be USD 3.2 billion by 2021.
The Orlistat market is segmented by the presence of leading pharmaceutical companies, the presence of healthcare professionals, and the presence of generic drug manufacturers. The presence of generic manufacturers is further supported by the fact that the market for the Orlistat is growing rapidly, with annual growth rates up to USD 1.
Orlistat, also known as Xenical, is a prescription weight loss medication that is commonly used to help people lose weight. It works by blocking the absorption of fat from the body, which helps to reduce calorie intake. It is available in pharmacies, and is usually taken by mouth with a meal. It is important to follow the directions provided by your healthcare provider or pharmacist, and to discuss the risks and benefits of taking Orlistat. It is also available as an over-the-counter weight loss aid, such as Slimming Capsules, which contains the active ingredient Orlistat, which works by blocking the absorption of fat in the body, helping to reduce calorie intake. It is important to note that Orlistat should only be taken by mouth and should not be taken with other medications, such as anti-diabetic medications or antidepressants. It is also important to consult with a healthcare professional before starting Orlistat, as they can provide a more accurate diagnosis and guide you on the proper use of this medication.
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